Fig. 2.

Calcineurin Aβ (CNAβ) deficiency decreases inflammation in transforming growth factor (TGF) β1 knock-out mice. Mice were killed and immersed in 10% neutral buffered formalin (NBF) for fixation after the lungs and gut were profused with 10% NBF. Formalin-fixed tissues were embedded in paraffin blocks; 5–10 µm sections were cut and haematoxylin and eosin-stained and analysed for inflammatory lesions by a pathologist. Inflammation score was determined as described in the text. Inflammation score in various organs of Tgfb1^−/−Cnab^+/− (a) and Tgfb1^−/−Cnab^−/− mice (b). Each mouse was represented by one symbol. Organs with no inflammation are not shown.