Table 2. Comparison of PrPres tissue distribution in TSE-affected ruminants*†.

Species (condition)	Brain	Spleen	Nodes	Tonsil	Natural transmission
Elk (CWD)	10/10	2/10	5/10	4/9	Low
Mule deer (CWD)	12/12	2/10	12/12	9/10	High
White-tailed deer (CWD)	3/3	1/3	3/3	2/3	High
Sheep‡ (scrapie)	8/8	7/8	6/8	Yes	High
Cattle (BSE)§	6/6	Neg	Neg	Neg	No

*PrPres, disease-associated prion protein; TSE, transmissible spongiform encephalopathy; CWD, chronic wasting disease; BSE, bovine spongiform encephalopathy; Neg, negative.
†Distribution of PrPres or infectivity in peripheral tissues of TSE affected ruminants was compared. Data for deer and elk were determined in the study presented here. Data for sheep are from an earlier publication (30) as are the data for cattle (14,15)
‡Data from (30).
§Data from (14).