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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Expert Opin Biol Ther. 2009 Aug;9(8):975–989. doi: 10.1517/14712590903052877

Fig 3.

Fig 3

(A) Internalization of PNATAR-CPP in HIV-1 virions. The HIV-1 virions incubated with I125-labeled PNATAR-CPP conjugate was subjected to discontinuous sucrose density gradient ultracentrifugation. Fractions collected from the bottom and analyzed for p24 antigen and for radioactivity [35].

(B) Abortive endogenous reverse transcription in HIV-1 virions pretreated with PNATAR-CPP conjugate [35]. Lane1, untreated HIV-1 virions; lanes 2 and 3, pre-treated with 1 μM and 2.5 μM of PNATAR Transportan conjugate, respectively; lanes 4 and 5, pre-treated with scrambled PNA-Transportan conjugate at 2 μM and 5 μM concentrations, respectively.