Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Footprinting of MLV integrase on terminal viral DNA. Footprinting was carried out as described in Materials and Methods. End-labeled primer SW6 (13) was used for PCR to detect the U5 viral DNA end. Strong enhancements are located at ≈20 bp from the tip of the U5 end. Controls are with naked viral DNA (lane 1) and MLV preintegration complexes (lane 2). Footprinting in the absence (lane 3) or presence (lane 4) of purified integrase is shown.
