Appendix.

Modified Total Neuropathy Score

Parameter	0	1	2	3	4
Pin sensibility	Normal	Reduced in fingers/toes	Reduced up to wrist/ankle	Reduced up to elbow/knee	Reduced to above elbow/knee
Vibration sensibility	Normal	Reduced in fingers/toes	Reduced up to wrist/ankle	Reduced up to elbow/knee	Reduced to above elbow/knee
Strength	Normal	Mild weakness	Moderate weakness	Severe weakness	Paralysis
Tendon Reflexes	Normal	Ankle reflex reduced	Ankle reflex absent	Ankle reflex absent, others reduced	All reflexes absent