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. Author manuscript; available in PMC: 2010 Jun 24.
Published in final edited form as: Brain Res. 2009 Mar 12;1277:70–83. doi: 10.1016/j.brainres.2009.02.079

Figure 7.

Figure 7

A. Basal turn EP versus compound action potential (CAP) thresholds in gerbils and mice. Old gerbils are compared with young mice within 24 hrs of severe noise exposure (4–45 kHz, 110 dB SPL, 2 hrs). Both relations show slopes near −0.4 to −0.5 dB/mV. B. Old CBA/CaJ mice also show a significant correlation. This may indicate that age-related hearing loss in both gerbils and CBA/CaJ primarily reflects EP decline. C. Because the required gain of the cochlear amplifier is greater at higher frequencies, EP reduction is expected to affect high frequency thresholds more than low. Comparison of CAP thresholds in old CBA/J and CBA/CaJ mice suggest this pattern applies to CBA/CaJ. Data in A are re-plotted from (Ohlemiller and Gagnon, 2007a; Schmiedt, 1993).