Skip to main content
. 2009 Dec 8;2009:576219. doi: 10.1155/2009/576219

Table 1.

Sex, age, islet-related autoantibody (IA-2A, IAA and GADA) profile, and associated disorders in 9 newly diagnosed T1D patients at disease onset. The diagnosis of T1D was done according to the WHO and the American Diabetes association (ADA) criteria. NT: not tested; pos: positive; neg: negative.

T1D patient Sex Age at onset (years) IA-2A (cut-off <1.1) IAA (cut-off <7%) GADA* (cut-off <3) Associated disorders
1 F 10.9 neg (0.1) neg (4) pos (63) desquamative dermatitis
2 M 10.0 pos (28) neg (4) pos (8.6) none
3 F 14.7 pos (20) pos (8) pos (13) anti-thyroid antibodies positive, mild obesity
4 F 12.6 pos (7.9) neg (4.7) pos (19) hypercolesterolemia
5 M 9.2 pos (3.6) pos (56) neg (0.1) none
6 M 16.4 pos (8) neg (4.7) neg (2.5) autoimmune thyroiditis, LT4 replacement therapy
7 M 11.8 neg (0.4) pos (74) pos (5.5) none
8 F 8.4 pos (1.3) pos (11) pos (1) none
9 F 9.4 pos (44) pos (16) pos (7) anti-thyroid antibodies positive

*Assay performed at San Raffaele Hospital, Milan, Italy. GADA and IA-2A measurements were performed by radiobinding assay with in vitro translated 35S-methionine-labeled GAD65 or IA-2 [31, 32]. IAA were measured using a competitive protein A/G insulin radiobinding assay [33].