Table 1.
MDACC Patient Demographic and Clinical Characteristics by HER2 Status
| Characteristic | HER2 Negative (n = 867) |
HER2 Positive (n = 98) |
P | ||
|---|---|---|---|---|---|
| No. | % | No. | % | ||
| Age, years | |||||
| Minimal | 26 | 28 | |||
| Median | 57 | 51.5 | |||
| Maximal | 87 | 78 | < .0001 | ||
| Ethnicity | |||||
| Black | 61 | 7.0 | 9 | 9.2 | |
| Hispanic | 78 | 9.0 | 10 | 10.2 | |
| Other | 35 | 4.0 | 4 | 4.1 | |
| White | 693 | 79.9 | 75 | 76.5 | .843 |
| Menopausal status | |||||
| Premenopausal | 201 | 23.2 | 43 | 43.9 | |
| Postmenopausal | 665 | 76.8 | 55 | 56.1 | < .0001 |
| Histology | |||||
| Other | 206 | 23.8 | 8 | 8.2 | |
| Ductal | 661 | 76.2 | 90 | 91.8 | .0004 |
| T stage | |||||
| Ia | 280 | 32.3 | 43 | 43.9 | |
| Ib | 587 | 67.7 | 55 | 56.1 | .021 |
| Hormone receptor status | |||||
| Negative | 125 | 14.4 | 38 | 38.8 | |
| Positive | 742 | 85.6 | 60 | 61.2 | < .0001 |
| Nuclear grade | |||||
| 1 | 116 | 17.3 | 1 | 1.5 | |
| 2 | 386 | 57.6 | 17 | 25.4 | |
| 3 | 168 | 25.1 | 49 | 73.1 | < .0001 |
Abbreviations: MDACC, M. D. Anderson Cancer Center; HER2, human epidermal growth factor receptor 2.