Table 3.

MDACC Multivariable Models

Comparative Variable	Multivariable Analyses by Survival Status
	Recurrence Free			Distant Recurrence–Free
	Hazard Ratio	95% CI	P	Hazard Ratio	95% CI	P
HER2 status
Positive v negative	2.68	1.44 to 5	.002	5.30	2.23 to 12.62	.0002
Hormone receptor status
Positive v negative	0.41	0.23 to 0.72	.002	0.59	0.25 to 1.37	.219
Age at diagnosis, years*	0.96	0.94 to 0.98	.001	0.73	0.32 to 1.7	.467
Tumor grade
3 v 1-2	1.34	0.75 to 2.41	.320	0.97	0.94 to 1	.080
Stage
Ib v Ia	1.59	0.91 to 2.78	.103	1.47	0.68 to 3.18	.329

Abbreviations: MDACC, M. D. Anderson Cancer Center; HER2, human epidermal growth factor receptor 2.

^*Continuous variable.