Table 2.

Toxicity Summary

Toxicity	Occurrences by Grade
	Gemcitabine and Carboplatin (n = 79)						Gemcitabine (n = 81)
	2		3		4		2		3		4
	No.	%	No.	%	No.	%	No.	%	No.	%	No.	%
Hematologic
Neutropenia	9	11.4	29	36.7	17	21.5	6	7.4	7	8.6	2	2.5
Anemia	19	24.1	12	15.2	0	0.0	19	23.5	5	6.2	1	1.2
Thrombocytopenia	5	6.3	14	17.7	21	26.6	3	3.7	3	3.7	0	0.0
Febrile neutropenia	—	—	0	0.0	0	0.0	—	—	0	0.0	0	0.0
Nonhematologic
Fatigue	19	24.1	3	3.8	0	0.0	15	18.5	13	16.0	2	2.5
Dyspnea	9	11.4	12	15.2	1	1.3	9	11.1	15	18.5	1	1.2
Anorexia	11	13.9	1	1.3	0	0.0	14	17.3	2	2.5	0	0.0
Nausea	9	11.4	0	0.0	0	0.0	8	9.9	2	2.5	0	0.0
Pneumonia	0	0.0	5	6.3	0	0.0	2	2.5	6	7.4	1	1.2
Dehydration	4	5.1	1	1.3	0	0.0	4	4.9	4	4.9	0	0.0
Diarrhea	3	3.8	0	0.0	0	0.0	4	4.9	3	3.7	0	0.0
Vomiting	4	5.1	0	0.0	0	0.0	3	3.7	2	2.5	0	0.0
Pleural effusion	1	1.3	4	5.1	0	0.0	1	1.2	2	2.5	0	0.0
Dizziness	4	5.1	1	1.3	0	0.0	2	2.5	0	0.0	0	0.0
Rash	3	3.8	0	0.0	0	0.0	1	1.2	0	0.0	0	0.0
Chest pain	0	0.0	2	2.5	0	0.0	2	2.5	1	1.2	1	1.2
Alopecia	2	2.5	—	—	—	—	0	0.0	—	—	—	—