Table 1. New and Old World distribution of pre-Columbian treponematoses cases, as evidenced by paleopathological research.
| Total cases | New World cases | Old World cases | Probable cases | Uncertain diagnosis or age | Total | |
| 6,000–1,000 BC | ||||||
| Treponematosis | 2 | 2 | 0 | 0 | 0 | 2 |
| Yaws | 6 | 5 | 1 | 1 | 1 | 8 |
| Bejel | 5 | 2 | 3 | 0 | 1 | 6 |
| Syphilis | 2 | 1 | 1 | 1 | 0 | 3 |
| Total | 15 | 10 | 5 | 2 | 2 | 19 |
| 1,000 BC–1,000 AD | ||||||
| Treponematosis | 8 | 5 | 3 | 1 | 1 | 10 |
| Yaws | 8 | 8 | 0 | 3 | 2 | 13 |
| Bejel | 7 | 3 | 4 | 0 | 0 | 7 |
| Syphilis | 6 | 5 | 1 | 4 | 1 | 11 |
| Total | 29 | 21 | 8 | 8 | 4 | 41 |
| 1,000 AD- Contact | ||||||
| Treponematosis | 21 | 7 | 14 | 2 | 5 | 28 |
| Yaws | 5 | 5 | 0 | 4 | 1 | 10 |
| Bejel | 3 | 2 | 1 | 1 | 0 | 4 |
| Syphilis | 16 | 11 | 5 | 3 | 7 | 26 |
| Total | 45 | 25 | 20 | 10 | 13 | 69 |
| Grand Total | 89 | 56 | 33 | 20 | 19 | 128 |
For references please refer to Table S1. Probable or uncertain cases were excluded from the quantification of treponematoses cases excavated in the New and Old World.