Table 1.
Characteristic | CEE(n = 209) |
CEE Placebo(n = 226) |
P | ||
---|---|---|---|---|---|
No. | % | No. | % | ||
Age group at screening, years | .36 | ||||
50-59 | 74 | 35.4 | 94 | 41.6 | |
60-69 | 87 | 41.6 | 89 | 39.4 | |
70-79 | 48 | 23.0 | 43 | 19.0 | |
Ethnicity | .21 | ||||
White | 91 | 43.5 | 84 | 37.2 | |
Black | 80 | 38.3 | 106 | 46.9 | |
Hispanic | 37 | 17.7 | 33 | 14.6 | |
Asian/Pacific Islander | 1 | 0.5 | 3 | 1.3 | |
Education | .69 | ||||
High school diploma/GED or less | 66 | 32.0 | 79 | 35.4 | |
School after high school | 93 | 45.1 | 92 | 41.3 | |
College or higher | 47 | 22.8 | 52 | 23.3 | |
Income, $ | .73 | ||||
< 35,000 | 119 | 60.7 | 131 | 62.4 | |
≥ 35,000 | 77 | 39.3 | 79 | 37.6 | |
Years since menopause | .14 | ||||
< 5 | 24 | 13.7 | 18 | 9.7 | |
5-< 10 | 23 | 13.1 | 20 | 10.8 | |
10-< 15 | 27 | 15.4 | 19 | 10.2 | |
≥ 15 | 101 | 57.7 | 129 | 69.4 | |
Years since hysterectomy | .06 | ||||
< 18 | 66 | 31.9 | 61 | 27.2 | |
18-< 25 | 60 | 29.0 | 89 | 39.7 | |
≥ 25 | 81 | 39.1 | 74 | 33.0 | |
Age at menarche, years | .97 | ||||
≤ 12 | 103 | 49.3 | 110 | 49.1 | |
> 12 | 106 | 50.7 | 114 | 50.9 | |
No. of term pregnancies | .22 | ||||
Never pregnant/never had term pregnancy | 20 | 9.8 | 22 | 9.8 | |
1-2 | 53 | 25.9 | 72 | 32.1 | |
3-4 | 88 | 42.9 | 75 | 33.5 | |
5+ | 44 | 21.5 | 55 | 24.6 | |
Duration of oral contraceptive use, years | .65 | ||||
Nonuser | 132 | 63.2 | 132 | 58.4 | |
< 5 | 48 | 23.0 | 55 | 24.3 | |
5-< 10 | 15 | 7.2 | 23 | 10.2 | |
10+ | 14 | 6.7 | 16 | 7.1 | |
Lifetime HRT duration, years | .84 | ||||
Never used | 128 | 61.2 | 137 | 60.6 | |
< 5 | 41 | 19.6 | 49 | 21.7 | |
≥ 5 | 40 | 19.1 | 40 | 17.7 | |
Years since last HRT use | .55 | ||||
Never used HRT | 128 | 61.2 | 137 | 60.6 | |
Current user/≤ 1 | 30 | 14.4 | 26 | 11.5 | |
> 1 | 51 | 24.4 | 63 | 27.9 | |
Family history of breast cancer (female) | 31 | 16.1 | 28 | 13.1 | .39 |
Prior bilateral oophorectomy | 69 | 35.9 | 76 | 38.0 | .67 |
BMI, kg/m2 | .59 | ||||
Normal (< 25.0) | 36 | 17.2 | 36 | 16.1 | |
Overweight (25.0-29.9) | 74 | 35.4 | 71 | 31.7 | |
Obese (≥ 30.0) | 99 | 47.4 | 117 | 52.2 | |
Physical activity (METs/wk) | .83 | ||||
Lower tertile | 98 | 51.9 | 109 | 52.4 | |
Middle tertile | 54 | 28.6 | 63 | 30.3 | |
Upper tertile | 37 | 19.6 | 36 | 17.3 | |
Smoking | .06 | ||||
Never smoked | 116 | 55.5 | 128 | 57.4 | |
Past smoker | 73 | 34.9 | 60 | 26.9 | |
Current smoker | 20 | 9.6 | 35 | 15.7 | |
Alcohol intake, g/d | .64 | ||||
Nondrinker | 125 | 62.8 | 128 | 59.8 | |
< 2.7 | 38 | 19.1 | 49 | 22.9 | |
≥ 2.7 | 36 | 18.1 | 37 | 17.3 |
NOTE. There were no statistically significant differences between treatment arms. Categories were chosen on the basis of distribution of the variable in the entire Women's Health Initiative data set.
Abbreviations: CEE, conjugated equine estrogen; GED, General Equivalency Diploma; HRT, hormone replacement therapy; BMI, body mass index; MET, metabolic equivalent tasks.