Fig. 2.
Rapamycin suppresses regenerating myofiber growth. Mouse TA muscles were injured by BaCl2 injection, followed by daily intraperitoneal injection of Rap (1 mg/kg) starting on day 7 AI. On the days indicated, the animals were euthanized and TA muscles were isolated and cryosectioned. A: TA muscle cross-sections were stained with H&E. Scale bar represents 50 μm. B: CSAs of regenerating myofibers were quantified. At least 100 regenerating myofibers were measured for each muscle section. The average results (n = 7 mice for each data point) are shown, with error bars representing SD. The control data (solid bars) are from Fig. 1B.