TABLE 2.
Spearman correlations between folate and uracil misincorporation (UrMis; in pg/μg DNA) measurements1
| Year 3 plasma folate2 (n = 94) | Year 3 RBC folate2 (n = 94) | |
| Year 3 plasma folate2 (n = 94) | — | 0.71 (P < 0.0001) |
| Year 33 UrMis in mucosa24 (n = 92) | −0.15 (P = 0.14) | −0.18 (P = 0.09) |
| Year 33 UrMis in WBC24 (n = 60) | 0.006 (P = 0.97) | 0.003 (P = 0.97) |
1
Analysis includes participants who received placebo or folic acid supplementation. RBC, red blood cell; WBC, white blood cell count.
2
All measurements as continuous variables.
3
Year 3 of this study was defined as the time of the surveillance colonoscopy ≈3 y after the qualifying examination.
4
Total sample size = 92 for rectal mucosa uracil measurements; total sample size = 60 for WBC uracil measurements.