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Genetic abnormalities in the β 2 m locus of the RCC52 epithelioid and fibroblast-like clonal sublines
| Morphological type of subline | Mutation(s) in the coding region of the β 2 m gene | Heterozygosity status at chromosome 15q21 STRs | |
|---|---|---|---|
| D15S-126 | D15S-209 | ||
| Epithelioid | delCT in codon 13 to 15 | Homozygous | LOH |
| Fibroblast-like | delG in codon 6 and delCT in codon 13 to 15 | Homozygous | ROH |
STRs short tandem repeats, LOH loss of heterozygosity, ROH retention of heterozygosity
