TABLE 1.
Quartile of plasma selenium, interval in μmol/L |
||||||
---|---|---|---|---|---|---|
Overall | 1st (0.60 to <0.98) | 2nd (0.98 to <1.08) | 3rd (1.08 to <1.20) | 4th (1.20 to 2.79) | P-trend | |
n | 250 | 253 | 271 | 268 | ||
Age, y | 40.8 ± 12.8 | 38.3 ± 12.8 | 38.1 ± 12.6 | 41.8 ± 13.0 | 45.0 ± 11.7 | <0.001 |
Gender/menopausal status, % | ||||||
Male | 48.5 | 42.9 | 49.5 | 47.2 | 54.4 | 0.12 |
Postmenopause female | 16.2 | 15.1 | 13.3 | 15.7 | 20.8 | 0.01 |
Premenopause female | 35.3 | 42.1 | 37.1 | 37.2 | 24.8 | 0.001 |
BMI, kg/m2 | 26.7 ± 5.0 | 26.1 ± 5.1 | 26.8 ± 5.6 | 26.7 ± 4.6 | 27.0 ± 4.5 | 0.38 |
Smoking status, % | ||||||
Current | 33.1 | 52.5 | 34.3 | 29.2 | 17.5 | <0.001 |
Former | 39.6 | 27.0 | 41.3 | 39.8 | 49.7 | 0.001 |
Never | 27.3 | 20.5 | 24.4 | 31.0 | 32.8 | 0.001 |
Physical activity score | 44.5 ± 8.2 | 44.4 ± 9.1 | 45.6 ± 9.9 | 44.2 ± 6.9 | 43.7 ± 6.3 | 0.09 |
Income group, (>£600/mo), % | 36.9 | 21.2 | 34.5 | 41.4 | 49.7 | <0.001 |
Education, (Higher education or degree), % | 31.8 | 21.5 | 30.1 | 32.7 | 42.5 | 0.001 |
Vitamin/mineral supplements, % | 39.1 | 34.5 | 39.2 | 34.8 | 48.2 | <0.001 |
Plasma selenium, μmol/L | 1.10 ± 0.19 | 0.88 ± 0.08 | 1.03 ± 0.03 | 1.13 ± 0.04 | 1.34 ± 0.17 | — |
Red blood cell selenium, μmol/L | 1.65 ± 0.40 | 1.44 ± 0.27 | 1.59 ± 0.32 | 1.69 ± 0.36 | 1.88 ± 0.49 | <0.001 |
Whole-blood GPx activity,2nmol·mg Hb−1·min−1 | 124.6 ± 29.9 | 117.5 ± 27.2 | 122.6 ± 28.7 | 128.6 ± 32.0 | 129.1 ± 29.8 | <0.001 |
Daily food energy, kJ | 7768.0 ± 2355.2 | 7469.7 ± 2340.5 | 7947.1 ± 2587.8 | 7714.9 ± 2354.8 | 7928.7 ± 2085.7 | 0.08 |
Total cholesterol intake, mg/d | 260.7 ± 119.3 | 238.3 ± 118.2 | 258.6 ± 113.5 | 264.9 ± 117.0 | 279.8 ± 125.3 | 0.004 |
Total fat intake, g/d | 74.9 ± 27.6 | 72.7 ± 26.8 | 77.2 ± 29.1 | 73.3 ± 27.4 | 76.3 ± 26.7 | 0.34 |
Poly/saturated fatty acids ratio |
0.45 ± 0.17 |
0.42 ± 0.16 |
0.43 ± 0.15 |
0.46 ± 0.16 |
0.49 ± 0.21 |
0.002 |
Values are survey-weighted means ± SD or percentages for continuous or categorical variables; n = 1,042.
GPx, glutathione peroxidase.