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. 2009 Oct 23;297(6):H2262–H2269. doi: 10.1152/ajpheart.00817.2009

Fig. 2.

Fig. 2.

Effect of peroxide scavengers on rotenone-elicited increases in the detection of peroxide and its inhibition of relaxation to hypoxia in BCA precontracted with 30 mM KCl. A: levels of peroxide detected by luminol chemiluminescence in the presence of horseradish peroxidase are increased by rotenone in BCA when compared with control arteries. The glutathione peroxidase mimetic ebselen (0.1 mM) essentially eliminates the detection of BCA peroxide in the absence or presence of rotenone (n = 7–17). B: ebselen reversed the inhibitory effect of rotenone on hypoxic relaxation in BCA precontracted with 30 mM KCl (n = 5–7). C: Peg-catalase partially reversed the inhibitory effect of rotenone on hypoxic relaxation in BCA precontracted with 30 mM KCl (n = 7).