Table 2.

Characteristic network parameters obtained by model simulations of hemodynamics and oxygen distribution using experimental diameters and diameters after simulated adaptation with different metabolic signaling modes

	Experimental Diameters	Simulated Diameter Adaptation
		Tissue Signaling	Wall Signaling	RBC Signaling
Network characteristics
Verr	0.61	0.73	0.60	0.81
Diaerr	0	0.50	0.38	0.68
Hcerr	0.51	0.65	0.58	0.92
OxDef, %	0.7	0.2	0.2	4.7
Vol, nl	44	43	42	35
Optimized adaptation parameters
km		1.30	0.80	0.64
kc		1.52	1.60	2.17
kp		0.90	0.35	0.65
ks		3.24	2.51	1.89
Pref, mmHg		115	95	92
Q˙ref, nl/min		0.007	0.012	0.012
Jref		4,822	4,925	5,537

See text for definitions of acronyms. For simulated adaptation, optimized values of adaptation parameters are given.