Table 2.
Tumor | Negative | Positive | Total |
Grade II | 7 | 32 | 39 |
Grade III | 8 | 33 | 41 |
GBM | 42 | 153 | 195 |
Total | 57 | 218 | 275 |
Tumor | Negative | Weak | Mod/Strong |
GBM | 42 | 91 | 62 |
TEM1 Neg/Weak (N = 156) |
TEM1 Mod/Strong (N = 93) | ||
Age (years) | |||
Mean | 54.8 | 49.1 | |
Median | 57.2 | 50.5 | |
SD | 15.2 | 15.5 |
NOTE: Positive staining as measured by ISH was defined as: weak or 10% of vessels; moderate or approximately 50% of vessels; and strong or nearly 100% of vessels. TEM1/endosialin expression inversely correlated with patient age in grade II-IV astrocytomas for which age data was available, p = 0.004, Mann-Whitney test. SD: standard deviation.