Table A.
Parameters as measured by Monsanto in subchronic toxicological studies in rats, sorted by organs. * data available only for MON 863; ** raw data not analyzed by Monsanto for MON863; # data available only for NK 603 and MON 810; ## raw data lacking in the original NK 603 and MON 810 reports from Monsanto, ? non understandable lack of data.
Parameters (total 83) | Units | Weeks | Abbreviations |
---|---|---|---|
Body Weight (Wt) | g | 14 | TBWEIGHT |
Adrenal (3) | |||
Adrenal Wt | g | 14 | ADRENAL |
Adrenal % Body Wt | % | 14 | ADRENAL_%Body |
Adrenal % Brain Wt | % | 14 | ADRENAL_%Brain |
Brain (2) | |||
Brain Wt | g | 14 | BRAIN |
Brain % Body Wt | % | 14 | BRAIN_%Body |
Bone marrow (22) | |||
White Blood Cell | x10E3/ µL | 5, 14 | WBC |
Platelet Count | x10E3/ µL | 5, 14 | PLT |
Absolute Neutrophils | x10E3/ µL | 5, 14 | ABS_NEUT |
Absolute Lymphocytes | x10E3/ µL | 5, 14 | ABS_LYMPH |
Absolute Monocytes | x10E3/ µL | 5, 14 | ABS_MONO |
Absolute Eosinophils | x10E3 /µL | 5, 14 | ABS_EOS |
Absolute Basophils | x10E3/ µL | 5, 14 | ABS_BASO |
Absolute Lar Uni Cell # | x10E3/ µL | 5, 14 | ABS_LUC |
Neutrophils ** | % | 5, 14 | NEUT |
Lymphocytes ** | % | 5, 14 | LYMPH |
Monocytes ** | % | 5, 14 | MONO |
Eosinophils ** | % | 5, 14 | EOS |
Basophils ** | % | 5, 14 | BASO |
Lar Uni cell # | % | 5, 14 | LUC |
Red Blood Cell | x10E6 µL | 5, 14 | RBC |
Hemoglobin Conc. | g/dL | 5, 14 | HGB |
Hematocrit | % | 5, 14 | HCT |
Mean Corpuscular Vol. | fL | 5, 14 | MCV |
Mean Corpuscular Hgb | pg | 5, 14 | MCH |
Mean Corpuscular Hgb Conc. | g/dL | 5, 14 | MCHC |
Absolute Reticulocyte Count * | x10E3/ µL | 5, 14 | ABS_RETIC |
Reticulocyte Count * | %RBC | 5, 14 | RETIC |
Liver (17) | |||
Liver Wt | g | 14 | LIVER |
Liver % Body Wt | % | 14 | LIVER_%Body |
Liver % Brain Wt | % | 14 | LIVER_%Brain |
Albumin | g/dL | 5, 14 | ALBUMIN |
Globulin | g/dL | 5, 14 | GLOBULIN |
Albumin/Globulin Ratio | - | 5, 14 | A/G_RATIO |
Alanine Aminotransferase | U/L | 5, 14 | SGPT_ALT |
Aspartate Aminotransferase | U/L | 5, 14 | SGOT_AST |
Alkaline Phosphatase /AMP | U/L | 5, 14 | ALKPHOS |
Total Protein | g/dL | 5, 14 | TOT_PROTEIN |
Gamma Glutamyl Transferase | U/L | 5, ? | GAMMA_GT |
Total Bilirubin | mg/dL | 5, 14 | TOT_BILI |
Direct Bilirubin | mg/dL | 5, 14 | DIR_BILI |
Cholesterol * | mg/dL | 5, 14 | CHOLEST |
Triglycerides * | mg/dL | 5, 14 | TRIGLY |
Individual Prothrombin Time | seconds | 14 | PT |
Activated Partial Thromboplastin Time | seconds | 14 | APTT |
Heart (3) | |||
Heart Wt | g | 14 | HEART |
Heart % Body Wt | % | 14 | HEART_%Body |
Heart % Brain Wt | % | 14 | HEART_%Brain |
Kidney (25) | |||
Kidney Wt | g | 14 | KIDNEY |
Kidney % Body Wt | % | 14 | KIDNEY_%Body |
Kidney % Brain Wt | % | 14 | KIDNEY_%Brain |
Urine Calcium | mg/dL | 5, 14 | U_CALCIUM |
Urine Creatinine | mg/dL | 5, 14 | U_CREAT |
Urine Protein | mg/dL | 5, 14 | U_PROTEIN |
Urine Phosphorus | mg/dL | 5, 14 | U_PHOS |
Urine Sodium | mmol/L | 5, 14 | U_SODIUM |
Urine Potassium | mmol/L | 5, 14 | U_POTASSIUM |
Urine Chloride | mmol/L | 5, 14 | U_CHLORIDE |
Urine Creatinine Clearance # | mL/min/100 g body wt | 5, 14 | U_CREAT_Clear |
Urine Sodium Excretion * | meq/time | 5, 14 | U_SOD_excr |
Urine Potassium Excretion * | meq/time | 5, 14 | U_POT_excr |
Urine Chloride Excretion * | meq/time | 5, 14 | U_CHLOR_excr |
Total Urine Volume | mL/ collection period | 5, 14 | U_TOTALVOL |
NA/K Ratio | - | 5, 14 | U_NA/K_RATIO |
Blood Urea Nitrogen | mg/dL | 5, 14 | BUN |
Calcium | mg/dL | 5, 14 | CALCIUM |
Creatinine | mg/dL | 5, 14 | CREAT |
Phosphorus | mg/dL | 5, 14 | PHOS |
Sodium | mmol/L | 5, 14 | SODIUM |
Potassium | mmol/L | 5, 14 | POTASSIUM |
Chloride | mmol/L | 5, 14 | CHLORIDE |
PH ## | U PH | 5, 14 | U_PH |
Specific Gravity ## | U SG | 5, 14 | U_SG |
Pancreas (1) | |||
Glucose | mg/dL | 5, 14 | GLUCOSE |
Gonads (6) | |||
Testis Wt | g | 14 | TESTIS |
Testis % Body Wt | % | 14 | TESTIS_%Body |
Testis % Brain Wt | % | 14 | TESTIS_%Brain |
Ovary Wt | g | 14 | OVARY |
Ovary % Body Wt | % | 14 | OVARY_%Body |
Ovary % Brain Wt | % | 14 | OVARY_%Brain |
Spleen (3) | |||
Spleen Wt | g | 14 | SPLEEN |
Spleen % Body Wt | % | 14 | SPLEEN_%Body |
Spleen % Brain Wt | % | 14 | SPLEEN_%Brain |