. 2009 Oct 5;587(Pt 22):5451–5467. doi: 10.1113/jphysiol.2009.178053

Table 3.

Measures of respiratory parameters before, during and after exposure to intermittent hypoxia

	OSA		Control
	Antioxidant	Placebo	Antioxidant	Placebo
Ventilation
Baseline (l min⁻¹)	16.8 ± 0.9	18.8 ± 2.1	14.9 ± 2.5	14.8 ± 0.5
Initial hypoxic episode (l min⁻¹)	29.0 ± 1.7	31.6 ± 3.0^§	24.3 ± 1.0	24.5 ± 0.9
Final hypoxic episode (l min⁻¹)	30.6 ± 2.0	36.9 ± 2.8^‡^§^†	26.9 ± 1.3^‡	27.7 ± 2.2^‡
End-recovery (l min⁻¹)	23.3 ± 1.4^*	29.3 ± 2.8^*^§^†	20.2 ± 1.3^*	20.4 ± 1.3^*
End-recovery (fraction of baseline)	1.40 ± 0.07^*	1.59 ± 0.07^*^§^†	1.36 ± 0.06^*	1.39 ± 0.09^*
Tidal volume
Baseline (ml)	1136.4 ± 77.6	1298.5 ± 114.4^§	1006.6 ± 52.6	1030.8 ± 52.1
Initial hypoxic episode (ml)	1849.7 ±136.4	2089.6 ± 200.6^§	1600.8 ± 78.9	1676.7 ± 102.9
Final hypoxic episode (ml)	1858.5 ± 135.0	2138.1 ± 182.0^§	1708.3 ± 97.8^‡	1626.9 ± 71.0
End-recovery (ml)	1452.3 ± 107.8^*	1672.7 ± 152.1^*^§	1360.8 ± 98.1^*	1339.7 ± 80.2^*
End-recovery (fraction of baseline)	1.30 ± 0.07^*	1.30 ± 0.05^*	1.34 ± 0.06^*	1.31 ± 0.07^*
Breathing frequency
Baseline (breaths min⁻¹)	15.3 ± 0.7	15.0 ± 0.9	15.4 ± 0.8	15.4 ± 0.8
Initial hypoxic episode (breaths min⁻¹)	16.3 ± 0.8	15.7 ± 0.8	15.8 ± 1.0	15.7 ± 1.2
Final hypoxic episode (breaths min⁻¹)	17.1 ± 1.1	18.5 ± 1.3^‡^†	16.6 ± 1.4^‡	18.2 ± 2.3^‡
End-recovery (breaths min⁻¹)	17.0 ± 1.1^*	18.3 ± 1.1^*^†	15.5 ± 0.9	16.2 ± 1.1
End-recovery (fraction of baseline)	1.10 ± 0.05(P= 0.07)^*	1.24 ± 0.06^*^§^†	1.02 ± 0.04	1.05 ± 0.03

Significantly different from baseline;

^§

significantly different from control;

^†

significantly different from antioxidant trial;

^‡

significantly different from initial hypoxic episode.