Figure 2. Proportion of time spent in each sleep/wake state (A), sleep onset latency (B), number of sleep episodes (C), and duration of sleep episodes (D) during room air breathing in control (n= 8) and NCT (n= 8) rats.

Note the increase in wakefulness and decrease in non-REM sleep in NCT rats compared to control, mainly due to decrease in duration of non-REM sleep episodes. In addition, NCT increased sleep onset latency and increased the number of non-REM sleep episodes, indicating sleep fragmentation given the reduced non-REM sleep time. Data are shown as means ±s.e.m.*P < 0.05 compared to control.