Table 2.
Odds ratios (OR) for a male birth among offspring from parents in the Michigan Long-Term PBB Study with enrollment serum PBB concentrations
N (%) | Crude^ | Unadjusted * | Adjusted ** | ||
---|---|---|---|---|---|
Exposure Variables (μg/L) | Offspring | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
Model 1 (Maternal enrollment PBB only): | |||||
Maternal PBB | 865 | ||||
< 3 | 477 (55) | 1.00 | 1.00 | 1.00 | |
≥ 3 | 388 (45) | 0.92 (0.70, 1.21) | 0.93 (0.72, 1.20) | 0.93 (0.72, 1.20) | |
Model 2 (Paternal enrollment PBB only): | |||||
Paternal PBB | 300 | ||||
< 6 | 160 (53) | 1.00 | 1.00 | 1.00 | |
≥ 6 | 140 (47) | 1.11 (0.70, 1.75) | 0.95 (0.65, 1.39) | 1.18 (0.76, 1.83) | |
Model 3 (Maternal and Paternal enrollment PBB combined): | |||||
Maternal PBB | Paternal PBB | 300 | |||
< 3 | < 6 | 120 (40) | 1.00 | 1.00 | 1.00 |
other combinations | 70 (23) | 0.99 (0.55, 1.79) | 0.84 (0.52, 1.37) | 0.92 (0.61, 1.40) | |
≥ 3 | ≥ 6 | 110 (37) | 1.35 (0.80, 2.28) | 1.14 (0.73, 1.79) | 1.43 (0.89, 2.29) |
^ Crude ORs are unadjusted for covariates or offspring born to the same mother or father
* ORs are unadjusted for covariates, but adjusted for offspring born to the same mother or father
** AORs are adjusted for covariates (Model 1 adjusted for year of offspring's birth; Models 2 and 3 adjusted for year of offspring's birth and paternal BMI as low and normal vs. high) and adjusted for offspring born to the same mother or father