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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Psychosom Med. 2009 Aug 6;71(8):821–827. doi: 10.1097/PSY.0b013e3181b39aa1

Table 4.

Association between depression and HRV indices of autonomic nervous system activity

Unadjusted mean Adjusted mean*
No Depression
BDI < 10
mean±s.e.m.
Depression
BDI ≥ 10
mean±s.e,m.
p a No Depression
BDI < 10
mean±s.e,m.
Depression
BDI ≥ 10
mean±s.e,m.
p
RMSSD (ms) 24.97 ± 2.44 15.25 ± 1.66 0.002 24.72 ± 2,19 15.85 ± 3.57 0.047
pNN50 (%) 5.61 ± 1.04 1.83 ± 0.77 0.006 5.64 ± 0.93 1.75 ± 1.51 0.040
SDNN (ms) 112.0 ± 6.13 107.4 ± 10.50 0.70 110.76 ± 6.27 110.86 ± 10.60 0.99
HF (ln.ms2) 4.27 ± 0.18 3.71 ± 0.21 0.087 4.27 ± 0.16 3.72 ± 0.27 0.092
LF (ln.ms2) 5.28 ± 0.22 5.08 ± 0.31 0.62 5.30 ± 0.21 5.03 ± 0.34 0.51
LF/HF 1.25 ± 0.03 1.37 ± 0.05 0.061 1.26 ± 0.03 1.35 ± 0.05 0.16
*

adjusted for age, sex, hypertension and diabetes status.

a

unadjusted p values were calculated using unpooled variances and adjusted degrees of freedom if homogeneity of variance was not present (i.e., Levene’s test for equivalence of variance p < 0.05; RMSSD and PNN50).