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. Author manuscript; available in PMC: 2009 Dec 15.
Published in final edited form as: Circ Cardiovasc Genet. 2008 Dec 1;1(2):133–140. doi: 10.1161/CIRCGENETICS.108.797704

Figure 4.

Figure 4

Serum phosphate levels and maximal renal tubular phosphate reabsorption in patients with GACI surviving beyond infancy. A, Serum phosphate levels available from 13 surviving patients. B, TmP/GFR levels available from 11 surviving patients. Normal serum phosphate levels in children between 1 and 3 years is 1.00 to 1.95 mmol/L, between 4 and 6 years is 1.05 to 1.80 mmol/L, and between 7 and 9 years is 0.95 to 1.75 mmol/L.22 TmP/GFR was calculated according to Brodehl et al23 using the formula TmP/GFR=Sp-(Up×Screa)/Ucrea. Normal TmP/GFR in children between 2 and 15 years is 1.15 to 2.44 mmol/L.24 The means of serum phosphate levels and the means of TmP/GFR levels of each surviving patient were significantly lower than the lowest reference values in patients older than 3 years of age (P=0.031 for serum phosphate and P=0.004 for TmP/GFR levels; Wilcoxon test for 2 paired samples).