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Time-limited digestion with Bal31 exonuclease (0 to 60 min, as indicated) of control phage lambda DNA (A) and phiIPLA88 DNA (B), followed by restriction enzyme digestion (EcoRI in panel A and PvuII in panel B). The arrows point to the two sequentially degraded fragments of the linear control DNA and phiIPLA88 DNA. M, molecular size marker (0.5 to 10 kbp). Sampling times are indicated in minutes.
