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. 2009 Oct 9;37(22):7360–7367. doi: 10.1093/nar/gkp821

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© The Author(s) 2009. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Average melting profiles of CpG and non-CpG associated promoters in human, relative to the transcription start site. As reference set, we used RIKEN CAGE (2 tags or greater) for the human ENCODE regions. Nine thousand five hundred and sixty seven profiles were averaged for CpG-associated promoters. Four thousand three hundred and sixty seven profiles were averaged for non-CpG-associated promoters. The average melting temperature for the ENCODE regions as a whole is 70°C, indicated by the dotted line.