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. 2009 Oct 20;37(22):7728–7740. doi: 10.1093/nar/gkp862

Figure 2.

Figure 2.

Bistable 26 nt DNA oligonucleotide. (A) Imino proton 1H NMR spectra of bistable DNA S1 (existing in a dynamic equilibrium of secondary structures S1′ and S1″) and of reference hairpins S1a and S1b. (B) Same for the 5-fluoro 2′-deoxyuridine modified bistable DNA S2 (S2' and S2″) and the corresponding reference hairpins S1a and S2b. (C) 1H decoupled 19F NMR spectra of S2 and the corresponding reference hairpin S2b and reference single strand 5′-d[ACC(dU5F)TCCG]. Conditions: 0.3 mM oligonucleotide, 25 mM sodium arsenate buffer, H2O/D2O = 9/1, pH 7.0, 300 K.