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IC50 values of Rce1p inhibitors observed with trypanosomal and human Rce1
| Species | Compound | Mean IC50 (μM) ± SEM |
|---|---|---|
| T. brucei | 1 | 3.24 ± 0.52 |
| 2 | 83.42 ± 7.18 | |
| 3 | 8.10 ± 3.21 | |
| 4 | 160.75 ± 14.21 | |
| 5 | 176.77 ± 34.16 | |
| 6 | 1.30 ± 0.07 | |
| 7 | 0.25 ± 0.22 | |
| 8 | 4.23 ± 1.46 | |
| 9 | 0.91 ± 0.13 | |
| H. sapiens | 7 | 2.38 ± 0.19 |
| 8 | 2.43 ± 0.77 |
