Figure 5.
Antibody-Dependent Cellular Cytotoxicity (ADCC) Assays. LNCaP (PSMA-positive) and DU145 (PSMA-negative) cells were treated with the ARM-P derivatives at the indicated concentrations, and cell death was measured with and without exposure to anti-DNP antibody (Ab, 24 µg/mL) and peripheral blood mononuclear cells (PBMC). Points represent the average of 4 measurements ± standard deviation. All depicted trends were observed on at least three separate occasions.