Table 1.
Nomenclature and Genomic Positions of Amastin Loci Used in This Study, Each Defined by Conserved Flanking Genes in Leishmania major.
| Range (kbp) |
Upstream Locus |
Downstream Locus |
|||||
| Locus | Chromosome | Identifier | Description | Identifier | Description | ||
| ama8Aa | 8 | 94 | 101 | LmjF08.0260 | Hypothetical protein (1) | LmjF08.0280 | Ribosomal protein L2 |
| ama8B | 8 | 286 | 386 | LmjF08.0660 | Serine/threonine protein kinase | LmjF08.0890 | Mitochondrial DNA polymerase beta (3) |
| ama17a | 17 | — | — | — | — | LmjF17.1030 | Hypothetical protein |
| ama18a | 18 | 190 | 194 | LmjF18.0450 | Serine carboxypeptidase | LmjF18.0460 | Tubulin-specific chaperone |
| ama24A | 24 | 444 | 454 | LmjF24.1240 | Hypothetical protein | LmjF24.1300 | DNAJ-domain protein (1) |
| ama24Ba | 24 | 780 | 769 | LmjF24.2130 | Ubiquitin-conjugating enzyme E2 | LmjF24.2100 | Hypothetical protein |
| ama28 | 28 | 516 | 521 | LmjF28.1380 | Haloacid dehalogenase-like protein | LmjF28.1410 | DNA polymerase kappa (1) |
| ama30 | 30 | 274 | 280 | LmjF30.0840 | Hypothetical protein | LmjF30.0880 | Adenosine kinase |
| ama31 | 31 | 153 | 154 | LmjF31.0440 | Cytoskeleton-associated protein CAP5.5 | LmjF31.0460 | Calpain-like cysteine peptidase |
| ama34A | 34 | 201 | 202 | LmjF34.0495 | Splicing factor ptsr1 interacting protein | LmjF34.0510 | Phosphoglycan beta 1,2 arabinosyltransferase |
| ama34B | 34 | 416 | 427 | LmjF34.0940 | Serine/threonine protein kinase (1) | LmjF34.1000 | Myosin IB heavy chain (1) |
| ama34Ca | 34 | 368 | 374 | LmjF34.0820 | Elongation factor 1-beta | LmjF34.0840 | Elongation factor 1-beta |
| ama34D | 34 | 484 | 483 | LmjF34.1090 | Dihydroxyacetonephosphate acetyltransferase | LmjF34.1070 | Hypothetical protein |
| ama34E | 34 | 867 | 710 | LmjF34.2000 | Pyroglutamyl-peptidase I | LmjF34.1555 | Ubiquitin-conjugating enzyme |
| ama34F | 34 | 1,285 | 1,282 | LmjF34.2780 | 40S ribosomal protein S19 protein (1) | LmjF34.2810 | Zinc carboxypeptidase |
| ama36 | 36 | 468 | 473 | LmjF36.1260 | Fructose-1,6-bisphosphate aldolase (1) | LmjF36.1290 | Hypothetical protein |
NOTE.—Where a flanking gene is followed by a number in parentheses, this signifies the number of nonconserved genes between the amastin and the flanking gene named. Ama17 was only found in Crithidia sp., and no upstream information was available in this instance.
a
Those loci were not present in L. major, but each locus was still defined by conserved flanking genes that were present in L. major.