Table 1.
Demographic characteristics and functional outcome of 56 patients with chronic idiopathic axonal polyneuropathy
| Variable/Instrument | MRS total n = 56 (100%) | MRS score 1 n = 19 (34%) | MRS score 2 n = 30 (54%) | MRS score 3 n = 7 (12%) | |
|---|---|---|---|---|---|
| Demographics | Age, years | 67.8 | 66.1 | 67.7 | 73 |
| (8.6) | (8.4) | (8.9) | (7.1) | ||
| Gender (male; female, n) | 45;11 | 15;4 | 25;5 | 5;2 | |
| Disease duration, years | 10.5 | 9 | 11 | 12.6 | |
| (6.5) | (6.4) | (6.8) | (5.6) | ||
| Arm functioning | Maximal isometric strength (HHD, z-score) | −0.1 | 0.4 | −0.2 | −0.7 |
| (0.9) | (0.7) | (0.8) | (1.1) | ||
| Sensory function (SMS, 0–28 points) | 28.0 | 28 | 27.5 | 26 | |
| (6 to 28) | (17 to 28) | (6 to 28) | (17 to 28) | ||
| Pain (n(%)) | 20 | 4 | 13 | 3 | |
| (36) | (21) | (43) | (43) | ||
| Dexterity (SODA, 0–108 points) | 105.0 | 106 | 102 | 96 | |
| (76 to 108) | (76 to 108) | (76 to 108) | (82 to 108) | ||
| Leg functioning | Maximal isometric strength (HHD, z-score) | −1.9 | −1.2 | −2.1 | −2.6 |
| (1.0) | (0.7) | (0.9) | (0.9) | ||
| Sensory function (SMS, 0–28 points) | 15.0 | 16 | 15 | 13 | |
| (4 to 28) | (9 to 28) | (5 to 22) | (4 to 18) | ||
| Pain (n(%)) | 43 | 15 | 24 | 4 | |
| (77) | (79) | (80) | (57) | ||
| Walking perf. (SWT, 0–150 10-m. courses) | 60.4 | 101.0 | 44.9 | 16.3 | |
| (44.6) | (37.9) | (32.3) | (14.8) | ||
| Use of walking aids (n(%)) | 18 | 1 | 11 | 6 | |
| (32) | (5) | (37) | (86) | ||
| Fatigue (FSS, 1–7 points) | 4.5 | 2.7 | 5.2 | 5.3 | |
| (1 to 7) | (1.0 to 5.4) | (1.6 to 7.0) | (1.6 to 7.0) | ||
| Balance (BBS, 0–56 points) | 54.0 | 56 | 54 | 22 | |
| (13 to 56) | (13 to 56) | (30 to 56) | (30 to 56) | ||
| Autonomy indoors (IPA, 0–4 points) | 1.0 | 0 | 1.0 | 1.1 | |
| (0 to 2.1) | (0 to 1.7) | (0 to 2.1) | (0.6 to 1.9) | ||
| Autonomy outdoors (IPA, 0–4 points) | 1.4 | 0.6 | 1.8 | 2.4 | |
| (0 to 3.4) | (0 to 1.6) | (0 to 2.8) | (1.4 to 3.4) |
Values are mean (SD) or median (range) unless stated otherwise
HHD, hand-held dynamometry; SMS, sensory modality score; SODA, sequential occupational dexterity assessment; SWT, modified shuttle walk test; FSS, fatigue severity scale; BBS, Berg Balance Scale; IPA, impact on participation and autonomy questionnaire; MRS, Modified Rankin Scale: 0 = no symptoms at all; 1 = no significant disability despite symptoms: able to carry out all usual duties and activities; 2 = slight disability: unable to carry out all previous activities but able to look after own affairs without assistance; 3 = moderate disability: requiring some help, but able to walk without assistance; 4 = moderately severe disability: unable to walk without assistance, and unable to attend to own bodily needs without assistance; 5 = severe disability: bedridden, incontinent, and requiring constant nursing care and attention