. 2009 Nov 24;39(1):104–111. doi: 10.1093/ageing/afp210

Table 2.

ORs and 95% CIs for associations between APOE allele/genotype and dementia

	Comparison using non-demented controls				Comparison using HF non-demented controls
	Adjusted^a		Adjusted^a and weighted^b		Adjusted^a		Adjusted^a and weighted^b
	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Allele
ε2	0.6	0.3–0.9	0.3	0.1–0.6	0.6	0.3–1.1	0.2	0.1–0.5
ε3	1.0		1.0		1.0		1.0
ε4	2.2	1.6–3.0	2.9	1.7–4.9	2.4	1.6–3.5	3.2	1.8–5.6
Genotype
ε2/ε2	0.5	0.0–5.7	0.3	0.1–1.7	0.1	0.0–6.0	0.1	0.0–0.4
ε2/ε3	0.6	0.3–1.1	0.2	0.1–0.7	0.7	0.3–1.4	0.3	0.1–0.8
ε2/ε4	0.6	0.2–2.3	0.2	0.0–1.3	1.2	0.3–5.4	0.6	0.2–2.1
ε3/ε3	1.0		1.0		1.0		1.0
ε3/ε4	2.3	1.5–3.6	3.6	1.8–7.3	2.1	1.3–3.5	3.1	1.4–6.5
ε4/ε4	5.0	1.9–13.0	7.9	1.6–39.2	9.1	3.0–27.2	18.1	4.9–67.0

For age group, sex, education and social class.

For study design and drop-out.