Table 2.

Initial treatment for Hoag patients with invasive cancer (including in situ bladder) diagnosed 1986-1991 (n = 5487) and 1992-1999 (n = 10,548). Data shown are percentages of patients receiving such therapy

Treatment	1986-1991	1992-1999	P
Surgery only	36.9	31.0	< .0001
Surgery + radiation therapy	9.0	8.3	.095
Radiation therapy only	8.5	7.0	.003
Systemic therapy only*	8.6	9.5	.082
Surgery + systemic therapy	9.3	10.8	.003
Radiation + systemic therapy	8.6	9.9	.004
Surgery, radiation & systemic therapy	6.7	11.9	.0008
Received a biologic therapy	1.7	6.7	< .0001
Received any systemic therapy	24.6	42.1	< .0001
No anticancer therapy	10.4	11.6	.019

^*Chemotherapy, hormonal therapy, biologic response modifier.