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. 2009 Dec 29;4(12):e8472. doi: 10.1371/journal.pone.0008472

Figure 4. MEF2C silencing prevents load-induced left ventricular hypertrophy.

Figure 4

Data from sham operated (SO) and aortic banded mice (7 to 15 days after transverse aortic constriction – TAC). Bar graphs indicating the echocardiographic values of (A) posterior wall thickness (LVWT), (B) diastolic diameter (LVEDD) and (C) fractional shortening (FS). The values of SO mice treated with siMEF2C or siGFP did not reach statistical significance, so they were averaged. (D) Bar graphs show the left ventricle mass/body mass ratio and (E) the average cardiomyocytes diameter. * p<0.05 vs SO; # p<0.05 vs TAC 7days siGFP; † p<0,05 vs TAC 15 days siGFP. A total of 9 mice were analyzed in each subgroup.