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Organ culture model. A 4mm punch biopsy of newborn foreskin (a) is pierced with an 18-gauge needle (b). Biomaterial is inserted into the barrel of the lumen (c), the needle is withdrawn, and the biopsy containing the implanted biomaterial is cultured at the air-medium interface (d). Modified from Fukano Y, et al., Wound Repair Regen, 14:486, 2006, with permission from the journal.
