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. 1998 Sep 1;95(18):10632–10636. doi: 10.1073/pnas.95.18.10632

Figure 1.

Figure 1

Defective maintenance of Hoxa7 expression in Mll−/− embryos. Whole mount in situ hybridization of E8.5 and E9 control and Mll−/− embryos (lateral views). (A) Hoxa7 expression in the presomitic mesoderm and neural plate of E8.5 wild-type embryos. (B) Hox-7 expression in E8.5 Mll knockout embryos. Arrows indicate the anterior most extent of Hoxa7 expression. (C) Hoxa7 expression in somites 15–18 and presomitic mesoderm in E9 Mll+/− embryos. (D) Absence of Hoxa7 expression in somites of E9 Mll−/− embryos. Faint expression was detected in Mll−/− embryos proximal to the allantois. Arrows point to the anterior boundary of somite 15 (prospective eleventh vertebrae).