Localization of LMO-2 RNA in E10.5 mouse embryos. (A) Expression of LMO-2 RNA is detected in the developing limb buds. This lateral view looks down on the dorsal surface of the forelimb (fl) and hindlimb (hl), with anterior to the left and posterior to the right. (B) Higher magnification looking at the distal edge of the forelimb in A reveals expression in a broad band centered on the D-V boundary (arrows and dotted line) and extending into the dorsal and ventral regions of the limb bud. A, anterior; P, posterior; D, dorsal; V, ventral.