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Effect of oxidative treatments on CrICL activity. Reduced CrICL (control) was incubated for 30 min in the presence of different oxidants as indicated. The reversibility of CrICL inactivation was assessed by incubation in the presence of 20 mm DTT (+DTT). Data are represented as mean percentage of maximal activity ± S.D. (n = 3–5). 100% corresponds to the initial activity of reduced ICL.
