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. 2009 Oct 29;284(52):36424–36430. doi: 10.1074/jbc.M109.017509

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© 2009 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — The effect of NAGly and NALAla on the GLYT2 EL4 mutants R531L, K532G, and I545L. A, an amino acid sequence alignment of GLYT1, GLYT2, and LeuT_Aa for EL4. B, NAGly concentration-dependent modulation of 30 μm glycine transport currents for GLYT2 (■), R531L (□), K532G (▴), I545L (○), and GLYT1 (●) (n ≥5/curve). C, NALAla concentration-dependent modulation of 30 μm glycine transport currents for GLYT2 (■), R531L (□), K532G (▴), I545L (○), and GLYT1 (●) (n ≥5/curve). For most concentration response curves, the S.E. errors were smaller than the symbols.