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. Author manuscript; available in PMC: 2011 Jan 30.
Published in final edited form as: Psychiatry Res. 2010 Jan 30;181(1):15–23. doi: 10.1016/j.pscychresns.2009.07.009

Figure 3. Distribution of brain activity during right-hand finger tapping.

Figure 3

Voxel-based maps of significant brain activity for controls (A) and chronic cocaine users (B). To extend the data analysis beyond motor-related regions of interest, contrast maps were made for each individual comparing brain activity associated with performing the task to periods of rest. These data were modeled across all subjects in order to get a voxel-based representation of brain areas being used to perform the task for each group. To determine the areas significantly activated during the task relative to rest for each subject a minimum cluster size was set at 25 voxels with a threshold of statistical significance was set at p < 0.005 for uncorrected values.