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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Shock. 2010 Jan;33(1):31–42. doi: 10.1097/SHK.0b013e3181c02c1f

Figure 11.

Figure 11

The de novo biosynthetic pathways for the synthesis of sphinganine 1-phosphate and sphingosine 1-phosphate. Note that sphingosine is formed after turnover of ceramide and after sphinganine metabolism. Sphinganine can either be phosphorylated to form sphinganine 1-phosphate or converted to dihydroceramide. The structural differences between sphinganine-1-phosphate and sphingosine-1-phosphate are also shown. The double bond in sphingosine 1-phosphate is lacking in sphinganine 1-phosphate (arrows).