Table 4.
Covariate | OR (95% CI) |
---|---|
Methotrexate (mg/week) | |
None | 1.0 (referent) |
2.5 – 7.5 | 1.23 (0.25 – 5.9) |
10 – 12.5 | 3.04 (0.70 – 13.29) |
≥ 15 | 2.37 (0.81 – 6.92) |
Anti-TNF use (referent to no use) | 0.82 (0.31 – 2.17) |
Body mass index | |
< 25 | 1.0 (referent) |
25–30 | 2.97 (0.77 – 11.41) |
> 30 | 3.09 (0.84 – 11.45) |
Current Tobacco use | 1.35 (0.40 – 4.55) |
History of liver disorder | 4.96 (0.95 – 25.90) |
Number of liver enzyme test blood draws*** | 1.22 (0.53 – 2.84) |
Alcohol use | |
None / occasional | 1.0 (referent) |
1–3 / week | 1.22 (0.46 – 3.24) |
≥ 1 / day | 2.18 (0.52 – 9.15) |
OR = Odds Ratio; PsA = psoriatic arthritis; RA = rheumatoid arthritis; BMI = body mass index
similar to Table 3, additional covariates adjusted for included age, gender, duration of disease, number of physician visits, NSAID use, recent hospitalization, an interaction term between PsA and alcohol, and folate supplementation
Defined as AST or ALT greater than the upper limit of the laboratory normal
during observation period