TABLE 2.
Patient Characteristics and Treatment Modalities
| Variable | All | <1 year | 1 to 3 | 3 to 5 | 5 to 20 | Pa | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N | (%) | N | (%) | N | (%) | N | (%) | N | (%) | ||
| Total | 6212 | 242 | 640 | 745 | 4585 | ||||||
| Sex | |||||||||||
| Female | 2931 | (47.6) | 125 | (51.7) | 301 | (47.0) | 362 | (48.6) | 2143 | (46.7) | 0.41 |
| Male | 3281 | (53.2) | 117 | (48.3) | 339 | (53.0) | 383 | (51.4) | 2442 | (53.3) | |
| Race | |||||||||||
| White | 5089 | (82.6) | 202 | (83.5) | 537 | (83.9) | 591 | (79.3) | 3759 | (82.0) | 0.28 |
| Black | 659 | (10.7) | 19 | (7.9) | 61 | (9.5) | 92 | (12.3) | 487 | (10.6) | |
| Others | 464 | (7.5) | 21 | (8.7) | 42 | (6.6) | 62 | (8.3) | 339 | (7.4) | |
| Histology | |||||||||||
| Astrocytoma | 4605 | (74.7) | 188 | (77.7) | 512 | (80.0) | 544 | (73.0) | 3361 | (73.3) | 0.0001 |
| Oligodendroglioma | 315 | (5.1) | 4 | (1.7) | 21 | (3.3) | 26 | (3.5) | 264 | (5.8) | |
| Mixed and unspecified gliomas | 1222 | (19.8) | 48 | (19.8) | 97 | (15.2) | 170 | (22.8) | 907 | (19.8) | |
| Neuroepithelial glial tumors of uncertain origin |
70 | (1.1) | 2 | (0.8) | 10 | (1.6) | 5 | (0.7) | 53 | (1.2) | |
| Grade | |||||||||||
| I | 2074 | (33.7) | 55 | (22.7) | 262 | (40.9) | 290 | (38.9) | 1467 | (32.0) | <0.0001 |
| II | 1345 | (21.8) | 48 | (19.8) | 131 | (20.5) | 129 | (17.3) | 1037 | (22.6) | |
| III | 485 | (7.9) | 22 | (9.1) | 28 | (4.4) | 41 | (5.5) | 394 | (8.6) | |
| IV | 552 | (9.0) | 29 | (12.0) | 20 | (3.1) | 36 | (4.8) | 467 | (10.2) | |
| Unknown | 1756 | (28.5) | 88 | (36.4) | 199 | (31.1) | 249 | (33.4) | 1220 | (26.6) | |
| Site | |||||||||||
| Cerebrum | 1979 | (32.1) | 85 | (35.1) | 138 | (21.6) | 145 | (19.5) | 1611 | (35.1) | <0.0001 |
| Cerebellum | 1118 | (18.1) | 7 | (2.9) | 128 | (20.0) | 180 | (24.2) | 803 | (17.5) | |
| Brain stem | 1217 | (19.8) | 26 | (10.7) | 110 | (17.2) | 197 | (26.4) | 884 | (19.3) | |
| Ventricles | 246 | (4.0) | 12 | (5.0) | 26 | (4.1) | 24 | (3.2) | 184 | (4.0) | |
| Spine | 254 | (4.1) | 8 | (3.3) | 44 | (6.9) | 18 | (2.4) | 184 | (4.0) | |
| NOS/Others | 1398 | (22.7) | 104 | (43.0) | 194 | (30.3) | 181 | (24.3) | 919 | (20.0) | |
| Histologic confirmation | |||||||||||
| Done | 5177 | (84.0) | 206 | (85.1) | 534 | (83.4) | 577 | (77.4) | 3860 | (84.2) | 0.27 |
| Not done | 1012 | (16.4) | 34 | (14.0) | 104 | (16.3) | 164 | (22.0) | 710 | (15.5) | |
| Unknown | 23 | (0.4) | 2 | (0.8) | 2 | (0.3) | 4 | (0.5) | 15 | (0.3) | |
| Radiation | |||||||||||
| EBRT | 2297 | (37.3) | 30 | (12.4) | 113 | (17.7) | 245 | (32.9) | 1909 | (41.6) | <0.0001 |
| None | 3727 | (60.5) | 204 | (84.3) | 509 | (79.5) | 474 | (63.6) | 2540 | (55.4) | |
| Others | 188 | (3.1) | 8 | (3.3) | 18 | (2.8) | 26 | (3.5) | 136 | (3.0) | |
| Surgery | |||||||||||
| None | 1196 | (19.4) | 52 | (21.5) | 135 | (21.1) | 191 | (25.6) | 818 | (17.8) | <0.0001 |
| Biopsy | 213 | (3.5) | 11 | (4.5) | 11 | (1.7) | 35 | (4.7) | 156 | (3.4) | |
| Partial Resection | 1328 | (21.6) | 59 | (24.4) | 173 | (27.0) | 139 | (18.7) | 957 | (20.9) | |
| NOS/unknown/others | 2044 | (33.2) | 90 | (37.2) | 179 | (28.0) | 201 | (27.0) | 1574 | (34.3) | |
| GTR | 1431 | (23.2) | 30 | (12.4) | 142 | (22.2) | 179 | (24.0) | 1080 | (23.6) | |
a
Chi-square test was used to compare variables in different age groups.
NOS, not otherwise specified; GTR, gross total resection; EBRT, external-beam radiotherapy.