Skip to main content
. Author manuscript; available in PMC: 2011 Feb 15.
Published in final edited form as: Biochem Pharmacol. 2010 Feb 15;79(4):565–574. doi: 10.1016/j.bcp.2009.09.020

Figure 6.

Figure 6

Nutlin-3 sensitizes AJ02-NM0 cells to treatment with the topoisomerase II inhibitors doxorubicin and etoposide, but not the thymidylate synthase inhibitor, 5FU. AJ02-NM0 cells were treated for 24 hours with the indicated drugs, with Nutlin-3 (20µM) or DMSO vehicle control (as indicated). Cell viability was measured using the CellTiter 96 Aqueous One kit (Promega). The mean viability of triplicate cultures are shown ± SD. *** indicates p < 0.001 as determined by a two-way ANOVA with a Bonferroni’s post test.