Figure 1.

Mean (±SEM) body weight, caloric intake, and water consumption of males did not vary as a function of creatine supplementation over 6 weeks (a–c). Separate one-way ANOVAs for weekly averages of daily water consumption indicate that rats given +4% creatine drank more water during week 1 (^**p<0.001 vs +0%, ^**p<0.008 vs +2%) and week 2 (^**p<0.007 vs +0%, ^*p<0.041 vs +2%), but this effect was no longer significant by the third week. There were no significant differences for the remainder of the study or during behavioral testing days.