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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Mol Genet Metab. 2010 Jan;99(1):62–71. doi: 10.1016/j.ymgme.2009.08.002

Figure 2.

Figure 2

GAG accumulation in Idua-W392X mice. (A) Increased urinary GAG excretion in Idua-W392X mice (W392X) compared to wild-type mice (WT). (B) Fold-increase in tissue GAG levels. Each bar represents the mean ± SD of the fold-increase in tissue GAGs in mutant mice relative to wild-type controls. The dashed line indicates the normalized wild-type levels. Each assay was performed using at least 5 mice. *p < 0.001 (W392X vs. WT in each age group); #p < 0.001 (W392X at 30-weeks-old vs. W392X at 5- or 10-weeks-old).