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Additional lysosomal enzyme activities in Idua-W392X mouse tissue lysates. β-D-glucuronidase (β-Gluc) and β-D-hexosaminidase (β-Hex) activities were measured. Each bar indicates the mean +/− standard deviation of the fold-increase in lysosomal enzyme specific activities in Idua-W392X tissue lysates relative to wild-type. Each assay was performed using at least four mice. The dashed, horizontal line indicates the normalized levels of wild-type activity.
