Table 2.
5 weeks |
10 weeks |
30 weeks |
||||
---|---|---|---|---|---|---|
WT (n=5) | W392X (n=5) | WT (n=7) | W392X (n=7) | WT (n=8) | W392X (n=8) | |
Brain | 3.24±0.24 | #4.01±0.36 | 2.53±0.45 | *3.86±1.25 | 2.80±0.27 | #4.50±0.51 |
Heart | 1.38±0.31 | #3.14±0.40 | 1.60±0.98 | #5.08±1.95 | 0.84±0.12 | #5.16±0.45 |
Kidney | 3.02±0.53 | #11.23±2.14 | 3.05±0.71 | #10.95±1.26 | 2.59±0.51 | #10.03±1.53 |
Liver | 1.38±0.20 | #10.38±0.86 | 1.23±0.32 | #11.79±2.04 | 1.11±0.13 | #19.62±2.80 |
Lung | 4.39±1.08 | #13.75±1.17 | 3.92±1.04 | #13.31±2.84 | 3.49±0.32 | #8.50±0.49 |
Spleen | 4.87±2.20 | *8.90±1.96 | 6.87±1.28 | #13.78±2.33 | 4.21±1.02 | #13.50±1.80 |
Tissue GAG values are represented as the mean ± SD of the micrograms of GAGs per milligram of defatted, dried tissue. n = number of mice.
p < 0.004,
p ≤ 0.02.