Table VII.
Rms values for the ligands docked to GPCRs (in Å)
Receptor | X-ray structure | Predicted loops with rms values: | |||
---|---|---|---|---|---|
without loops | with loops | best | average | worst | |
β2AR | 0.96 | 3.40 | 0.89 | 1.12 | 1.30 |
β1AR | 0.58 | 2.30 | 0.59 | 1.06 | 1.10 |
A2AR | 2.89 | 3.54 | 3.56 | 6.56 | ≫10 |